Subclinical Thyroid Disease

ContextPatients with serum thyroid-stimulating hormone (TSH) levels outside the reference range and levels of free thyroxine (FT4) and triiodothyronine (T3) within the reference range are common in clinical practice. The necessity for further evaluation, possible treatment, and the urgency of treatment have not been clearly established.ObjectivesTo define subclinical thyroid disease, review its epidemiology, recommend an appropriate evaluation,...