Total flavonoid fraction of rhizoma drynaria improves bone properties in ovariectomized mice and exerts estrogen-like activities in rat osteoblast-like (UMR-106) cells
Abstract
Rhizoma Drynaria (RD) has been widely used for healing bone fractures or related diseases in traditional Chinese medicine. The present study was designed to determine if RD total flavonoids (RDTF) could exert estrogen-like protective actions on bone. Young C57/BL6J mice were ovariectomized (OVX) and treated orally with RDTF (0.087, 0.173 or 0.346 mg/g/day), 17β-estradiol (2μg/g/day) or its vehicle for 6 weeks. Bone mineral densities (BMD) was...
Paper Details
Title
Total flavonoid fraction of rhizoma drynaria improves bone properties in ovariectomized mice and exerts estrogen-like activities in rat osteoblast-like (UMR-106) cells
Published Date
Jul 14, 2020
Volume
20
Issue
1
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