Overexpressed proprotein convertase 1/3 induces an epithelial-mesenchymal transition in airway epithelium

Volume: 42, Issue: 5, Pages: 1379 - 1390
Published: Jan 11, 2013
Abstract
The proprotein convertases (PCs) are serine proteases responsible for the proteolytic maturation of many precursor proteins involved in upper airway remodelling during nasal polyposis. We have previously found that PC1/3 is expressed in human nasal mucosa. However, whether PC1/3 is related to nasal polyp formation has not been investigated. To gain insight into the functional role of PC1/3 in nasal polyps, we determined PC1/3 expression in nasal...
Paper Details
Title
Overexpressed proprotein convertase 1/3 induces an epithelial-mesenchymal transition in airway epithelium
Published Date
Jan 11, 2013
Volume
42
Issue
5
Pages
1379 - 1390
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