The hmu locus of Yersinia pestis is essential for utilization of free haemin and haem‐protein complexes as iron sources

Volume: 20, Issue: 4, Pages: 725 - 739
Published: May 1, 1996
Abstract
Summary Yersinia pestis strains utilize haem and several haem-protein complexes as sole sources of iron. In this study, the haemin uptake locus (hmu) of Y. pestis KIM6+ was selected from a genomic library by trans-duction into an Escherichia coli siderophore synthesis (entC) mutant. Recombinant plasmids containing a common 16 kb BamHI insert were isolated that allowed E. coli entC to use haemin as an iron source. An 8.6 kb region of this insert...
Paper Details
Title
The hmu locus of Yersinia pestis is essential for utilization of free haemin and haem‐protein complexes as iron sources
Published Date
May 1, 1996
Volume
20
Issue
4
Pages
725 - 739
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