Quantitative Analysis of Dynamic Contrast-Enhanced MR Images Based on Bayesian P-Splines
Volume: 28, Issue: 6, Pages: 789 - 798
Published: Jan 1, 2009
Abstract
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is an important tool for detecting subtle kinetic changes in cancerous tissue. Quantitative analysis of DCE-MRI typically involves the convolution of an arterial input function (AIF) with a nonlinear pharmacokinetic model of the contrast agent concentration. Parameters of the kinetic model are biologically meaningful, but the optimization of the nonlinear model has significant...
Paper Details
Title
Quantitative Analysis of Dynamic Contrast-Enhanced MR Images Based on Bayesian P-Splines
Published Date
Jan 1, 2009
Volume
28
Issue
6
Pages
789 - 798
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