Plasma Caffeic Acid Is Associated with Statistical Clustering of the Anticolitic Efficacy of Caffeic Acid in Dextran Sulfate Sodium-Treated Mice
Abstract
We hypothesized that interindividual variability in the bioavailability of caffeic acid (CA) would influence its anticolitic efficacy and that mice may be appropriate for modeling human gut microbial metabolism of CA, which is thought to influence CA bioavailability. Anaerobic human fecal and mouse cecal sample mixtures were incubated with CA derivatives from Echinacea purpurea and compound disappearance rates were measured, which were similar...
Paper Details
Title
Plasma Caffeic Acid Is Associated with Statistical Clustering of the Anticolitic Efficacy of Caffeic Acid in Dextran Sulfate Sodium-Treated Mice
Published Date
Nov 1, 2011
Journal
Volume
141
Issue
11
Pages
1989 - 1995
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