Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring

Volume: 586, Issue: 8, Pages: 2231 - 2244
Published: Apr 14, 2008
Abstract
Early embryonic development is known to be susceptible to maternal undernutrition, leading to a disease‐related postnatal phenotype. To determine whether this sensitivity extended into oocyte development, we examined the effect of maternal normal protein diet (18% casein; NPD) or isocaloric low protein diet (9% casein; LPD) restricted to one ovulatory cycle (3.5 days) prior to natural mating in female MF‐1 mice. After mating, all females...
Paper Details
Title
Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring
Published Date
Apr 14, 2008
Volume
586
Issue
8
Pages
2231 - 2244
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