Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis
Abstract
Autophagy is a major catabolic process responsible for the delivery of proteins and organelles to the lysosome/vacuole for degradation. Malfunction of this pathway has been implicated in numerous pathological conditions. Different organelles have been found to contribute to the formation of autophagosomes, but the exact mechanism mediating this process remains obscure. Here, we show that lipid droplets (LDs) are important for the regulation of...
Paper Details
Title
Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis
Published Date
Jul 14, 2015
Journal
Volume
34
Issue
16
Pages
2117 - 2131
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Notes
History