Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
Abstract
Evidence for the potent influence of stromal organization and function on invasion and metastasis of breast tumors is ever growing. We have performed a rigorous examination of the relationship of a tumor-associated collagen signature-3 (TACS-3) to the long-term survival rate of human patients. TACS-3 is characterized by bundles of straightened and aligned collagen fibers that are oriented perpendicular to the tumor boundary. An evaluation of...
Paper Details
Title
Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
Published Date
Mar 1, 2011
Volume
178
Issue
3
Pages
1221 - 1232
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