Proliferation and Differentiation of Cultured MC3T3-E1 Osteoblasts on Surface-layer Modified Hydroxyapatite Ceramic with Acid and Heat Treatments
Abstract
Effects of functionally gradient calcium phosphate consisting of hydroxyapatite (HAP) and alpha-tricalcium phosphate (alpha-TCP) on proliferation and differentiation of osteoblasts were evaluated using MC3T3-E1 cells. There were no significant differences in the proliferation of MC3T3-E1 cells among HAP-alpha-TCP functionally gradient calcium phosphate, pure HAP, and cell culture plastic wells. mRNA expressions of type I collagen, alkaline...
Paper Details
Title
Proliferation and Differentiation of Cultured MC3T3-E1 Osteoblasts on Surface-layer Modified Hydroxyapatite Ceramic with Acid and Heat Treatments
Published Date
Jan 1, 2005
Journal
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