Decreased Conversion of 25-hydroxyvitamin D3 to 24,25-dihydroxyvitamin D3 Following Cholecalciferol Therapy in Patients with CKD

Volume: 9, Issue: 11, Pages: 1965 - 1973
Published: Nov 1, 2014
Abstract
Background and objectives Elevated concentrations of fibroblast growth factor 23 (FGF23) are postulated to promote 25-hydroxyvitamin D (25[OH]D) insufficiency in CKD by stimulating 24-hydroxylation of this metabolite, leading to its subsequent degradation; however, prospective human studies testing this relationship are lacking. Design, setting, participants, & measurements An open-label prospective study was conducted from October 2010 through...
Paper Details
Title
Decreased Conversion of 25-hydroxyvitamin D3 to 24,25-dihydroxyvitamin D3 Following Cholecalciferol Therapy in Patients with CKD
Published Date
Nov 1, 2014
Volume
9
Issue
11
Pages
1965 - 1973
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