Microblister Formation in Vesicant-Exposed Pig Skin

Six pigs were cutaneously exposed for 1 hr to high doses of sulfur mustard (HD) by both direct droplet contact and indirect vapor. Tissue was harvested for microscopic examination after 72 hr. Three other pigs were cutaneously exposed to HD and lewisite (L) by droplet streak application. Histologically, all test subjects exhibited microvesicle formations of varying intensities. Vapor exposures produced diffuse lesions of lesser severity than...