Cidea promotes hepatic steatosis by sensing dietary fatty acids
Abstract
High levels of dietary saturated fat have been closely associated with the development of hepatic steatosis, but the factors that mediate this process remain elusive. Here, we observed that the level of cell death-inducing DNA fragmentation factor-alpha-like effector a (Cidea) expression was highly correlated with the severity of hepatic steatosis in humans. Overexpression of Cidea in mouse liver resulted in increased hepatic lipid accumulation...
Paper Details
Title
Cidea promotes hepatic steatosis by sensing dietary fatty acids
Published Date
Jul 1, 2012
Journal
Volume
56
Issue
1
Pages
95 - 107
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Notes
History