Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
Abstract
An improvement in overall survival among patients with metastatic melanoma has been an elusive goal. In this phase 3 study, ipilimumab — which blocks cytotoxic T-lymphocyte–associated antigen 4 to potentiate an antitumor T-cell response — administered with or without a glycoprotein 100 (gp100) peptide vaccine was compared with gp100 alone in patients with previously treated metastatic...
Paper Details
Title
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
Published Date
Aug 19, 2010
Volume
363
Issue
8
Pages
711 - 723
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