In Vitro Activities of Daptomycin, Vancomycin, and Penicillin against Clostridium difficile , C. perfringens , Finegoldia magna , and Propionibacterium acnes

Daptomycin has in vitro activity against gram-positive anaerobic bacteria, although limited numbers of species have been tested. We studied the in vitro activities of daptomycin, vancomycin, and penicillin against more than 100 strains each of Clostridium difficile , C. perfringens , Finegoldia magna , and Propionibacterium acnes . Daptomycin Etest MICs and results from time-kill studies were determined for selected strains. For 392 of 421...