FAST IMAGE RECONSTRUCTION METHODS FOR FULLY 3D MULTISPECTRAL OPTICAL BIOLUMINESCENCE TOMOGRAPHY

We investigate fast iterative image reconstruction methods for fully 3D multispectral optical bioluminescence tomography where inhomogeneous optical properties are modeled using the finite element method (FEM). We compare two approaches to incorporating the forward model into the solution of the inverse problem. In the direct calculation approach we compute the full forward model by repeated solution of the PEM problem, once for each potential...