Edoxaban versus warfarin in patients with atrial fibrillation

Volume: 369, Issue: 22, Pages: 2093 - 2104
Published: Nov 27, 2013
Abstract
The annualized rate of the primary end point during treatment was 1.50% with warfarin (median time in the therapeutic range, 68.4%), as compared with 1.18% with high-dose edoxaban (hazard ratio, 0.79; 97.5% confidence interval [CI], 0.63 to 0.99; P<0.001 for noninferiority) and 1.61% with low-dose edoxaban (hazard ratio, 1.07; 97.5% CI, 0.87 to 1.31; P = 0.005 for noninferiority). In the intention-to-treat analysis, there was a trend favoring...
Paper Details
Title
Edoxaban versus warfarin in patients with atrial fibrillation
Published Date
Nov 27, 2013
Volume
369
Issue
22
Pages
2093 - 2104
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