Inflammatory effects of inhaled sulfur mustard in rat lung
Abstract
Inhalation of sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung damage, is a significant threat to both military and civilian populations. The mechanisms mediating its cytotoxic effects are unknown and were investigated in the present studies. Male rats Crl:CD(SD) were anesthetized, and then intratracheally intubated and exposed to 0.7-1.4mg/kg SM by vapor inhalation. Animals were euthanized 6, 24, 48h or 7days...
Paper Details
Title
Inflammatory effects of inhaled sulfur mustard in rat lung
Published Date
Oct 15, 2010
Volume
248
Issue
2
Pages
89 - 99
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