Liver enzymes and risk of cardiovascular disease in the general population: A meta-analysis of prospective cohort studies

Background Gamma glutamyltransferase (GGT), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP), commonly used markers of liver dysfunction, have been implicated with risk of cardiovascular disease (CVD). However, the strength and consistency of their associations in the general population have not been reliably quantified. Methods We synthesized available prospective epidemiological data on the...