Extracellular proteases are key mediators of S taphylococcus aureus virulence via the global modulation of virulence‐determinant stability
Abstract
Staphylococcus aureus is a highly virulent and successful pathogen that causes a diverse array of diseases. Recently, an increase of severe infections in healthy subjects has been observed, caused by community-associated methicillin-resistant S. aureus (CA-MRSA). The reason for enhanced CA-MRSA virulence is unclear; however, work suggests that it results from hypersecretion of agr-regulated toxins, including secreted proteases. In this study, we...
Paper Details
Title
Extracellular proteases are key mediators of S taphylococcus aureus virulence via the global modulation of virulence‐determinant stability
Published Date
Dec 11, 2012
Journal
Volume
2
Issue
1
Pages
18 - 34
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