Clinical prediction rules for pulmonary embolism: a systematic review and meta-analysis

Pretest probability assessment is necessary to identify patients in whom pulmonary embolism (PE) can be safely ruled out by a negative D-dimer without further investigations.Review and compare the performance of available clinical prediction rules (CPRs) for PE probability assessment.We identified studies that evaluated a CPR in patients with suspected PE from Embase, Medline and the Cochrane database. We determined the 95% confidence intervals...