The transcriptional and signalling networks of pluripotency
Abstract
Pluripotency and self-renewal are the hallmarks of embryonic stem cells. This state is maintained by a network of transcription factors and is influenced by specific signalling pathways. Current evidence indicates that multiple pluripotent states can exist in vitro. Here we review the recent advances in studying the transcriptional regulatory networks that define pluripotency, and elaborate on how manipulation of signalling pathways can modulate...
Paper Details
Title
The transcriptional and signalling networks of pluripotency
Published Date
May 1, 2011
Journal
Volume
13
Issue
5
Pages
490 - 496
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