Novel Ubiquitin-derived High Affinity Binding Proteins with Tumor Targeting Properties

Volume: 289, Issue: 12, Pages: 8493 - 8507
Published: Mar 21, 2014
Abstract
Targeting effector molecules to tumor cells is a promising mode of action for cancer therapy and diagnostics. Binding proteins with high affinity and specificity for a tumor target that carry effector molecules such as toxins, cytokines, or radiolabels to their intended site of action are required for these applications. In order to yield high tumor accumulation while maintaining low levels in healthy tissues and blood, the half-life of such...
Paper Details
Title
Novel Ubiquitin-derived High Affinity Binding Proteins with Tumor Targeting Properties
Published Date
Mar 21, 2014
Volume
289
Issue
12
Pages
8493 - 8507
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