Validating biomarkers of treatable mechanisms in irritable bowel syndrome

Background A valid biomarker is ‘an indicator of normal biologic or pathogenic processes, or pharmacological responses to a therapeutic intervention’. There is no validated biomarker for irritable bowel syndrome ( IBS ). The aim of the study was to assess ability of three quantitative traits to identify treatable processes to discriminate between IBS ‐diarrhea ( IBS ‐D) patients, IBS ‐constipation ( IBS ‐C) patients and healthy volunteers ( HV...