Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro.

Volume: 15, Issue: 12, Pages: 1469 - 1483
Published: Dec 1, 2013
Abstract
null Background aims null Multipotent mesenchymal stromal cells (MSCs) are clinically useful because of their immunomodulatory and regenerative properties, but MSC therapies are limited by the loss of self-renewal and cell plasticity associated with null ex vivo null expansion culture and, on transplantation, increased immunogenicity from xenogen exposure during culture. Recently, pooled human platelet lysate (hPL) has been used as a culture...
Paper Details
Title
Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro.
Published Date
Dec 1, 2013
Volume
15
Issue
12
Pages
1469 - 1483
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