Coupling of therapeutic molecules onto surface modified coralline hydroxyapatite

Surface modification and coupling of therapeutic molecules, tetracycline, onto coralline hydroxyapatite (CHA) and their in vitro evaluations were described in this study. Initially, CHA was graft polymerized with glycidylmethacrylate (GMA) using redox initiators and subsequently coupled to tetracycline through epoxy groups. The CHA grafted with polyGMA (CHA-g-PGMA) was characterized by Fourier transform infrared spectroscopy and powder X-ray...