Therapeutic approaches to dermatotoxicity by sulfur mustard I. Modulation of sulfur mustard-induced cutaneous injury in the mouse ear vesicant model†**

The mouse ear edema model is recognized for its usefulness in studying skin responses and damage following exposure to chemical irritants, and for evaluating pharmacological agents against chemically induced skin injury. We recently modified the mouse ear edema model for use with sulfur mustard (HD) and used this model to study the protective effect of 33 topically applied compounds comprising five pharmaceutical strategies (anti-inflammatories,...