Effect of prostaglandin I2 analogs on monocyte chemoattractant protein-1 in human monocyte and macrophage
Abstract
Chemokines play essential roles during inflammatory responses and in pathogenesis of inflammatory diseases. Monocyte chemotactic protein-1 (MCP-1) is a critical chemokine in the development of atherosclerosis and acute cardiovascular syndromes. MCP-1, by its chemotactic activity, causes diapedesis of monocytes from the lumen to the subendothelial space that leads to atherosclerotic plaque formation. Prostaglandin I2 (PGI2) analogs are used...
Paper Details
Title
Effect of prostaglandin I2 analogs on monocyte chemoattractant protein-1 in human monocyte and macrophage
Published Date
Aug 26, 2014
Volume
15
Issue
3
Pages
245 - 253
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