Systematic review of levodopa dose equivalency reporting in Parkinson's disease
Abstract
Interpretation of clinical trials comparing different drug regimens for Parkinson's disease (PD) is complicated by the different dose intensities used: higher doses of levodopa and, possibly, other drugs produce better symptomatic control but more late complications. To address this problem, conversion factors have been calculated for antiparkinsonian drugs that yield a total daily levodopa equivalent dose (LED). LED estimates vary, so we...
Paper Details
Title
Systematic review of levodopa dose equivalency reporting in Parkinson's disease
Published Date
Nov 10, 2010
Journal
Volume
25
Issue
15
Pages
2649 - 2653
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