Probing the relevance of 3D cancer models in nanomedicine research
Abstract
For decades, 2D cell culture format on plastic has been the main workhorse in cancer research. Though many important understandings of cancer cell biology were derived using this platform, it is not a fair representation of the in vivo scenario. In this review, both established and new 3D cell culture systems are discussed with specific references to anti-cancer drug and nanomedicine applications. 3D culture systems exploit more realistic...
Paper Details
Title
Probing the relevance of 3D cancer models in nanomedicine research
Published Date
Dec 1, 2014
Volume
79-80
Pages
95 - 106
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