Chitosan-coated PLGA nanoparticles: A sustained drug release strategy for cell cultures
Abstract
A recently patented one-step methodology was used for the formulation of chitosan (CS) coated polylactic-co-glycolic acid (PLGA) nanoparticles containing dexamethasone (DXM) as a model drug. SEM investigations showed that nanoparticles (NPs) were spherical in shape with smooth surface. CS coating switched NPs ζ-potential from negative to positive, without modifying particle size distribution. Moreover, CS coating allowed a significant modulation...
Paper Details
Title
Chitosan-coated PLGA nanoparticles: A sustained drug release strategy for cell cultures
Published Date
Mar 1, 2013
Volume
103
Pages
310 - 317
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