Metabonomic Evaluation of Melamine-Induced Acute Renal Toxicity in Rats
Abstract
The recent outbreak of renal failure in infants in China has been determined to be caused by melamine (Mel) and derivatives adulterated in the food. A metabonomic study was performed to evaluate the global biochemical alteration triggered by Mel ingestion in parallel with the acute renal toxicity in rats. Mel at 600, 300, and 100 mg/kg, cyanuric acid (Cya) at 100 mg/kg, and mixture of Mel and Cya (50 mg/kg each) were administered in five groups...
Paper Details
Title
Metabonomic Evaluation of Melamine-Induced Acute Renal Toxicity in Rats
Published Date
Jun 10, 2009
Journal
Volume
9
Issue
1
Pages
125 - 133
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