Adenovirus-Mediated eNOS Expression Augments Liver Injury after Ischemia/Reperfusion in Mice
Abstract
Hepatic ischemia/reperfusion (l/R) injury continues to be a critical problem. The role of nitric oxide in liver I/R injury is still controversial. This study examines the effect of endothelial nitric oxide synthase (eNOS) over-expression on hepatic function following I/R. Adenovirus expressing human eNOS (Ad-eNOS) was administered by tail vein injection into C57BL/6 mice. Control mice received either adenovirus expressing LacZ or vehicle only....
Paper Details
Title
Adenovirus-Mediated eNOS Expression Augments Liver Injury after Ischemia/Reperfusion in Mice
Published Date
Mar 25, 2014
Journal
Volume
9
Issue
3
Pages
e93304 - e93304
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