What made sesquiterpene lactones reach cancer clinical trials
Abstract
Sesquiterpene lactones (SLs) are plant-derived compounds often used in traditional medicine against inflammation and cancer. This review focuses on the chemical and biological properties of SLs that lead to enhanced anticancer and anti-inflammatory effects. The chemical properties comprise alkylating center reactivity, lipophilicity, and molecular geometry and electronic features. SLs in clinical trials are artemisinin, thapsigargin and...
Paper Details
Title
What made sesquiterpene lactones reach cancer clinical trials
Published Date
Aug 1, 2010
Journal
Volume
15
Issue
15
Pages
668 - 678
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