Down-regulation of N-methyl D-aspartate receptor in rat-modeled disuse osteopenia

Volume: 16, Issue: 12, Pages: 1780 - 1788
Published: Jul 5, 2005
Abstract
Lack of mechanical stress may result in osteoporosis; however, the underlying mechanisms of disuse osteoporosis remain unclear. It has been indicated that mechanical loading causes extracellular glutamate accumulation in osteoblasts. We hypothesized that the glutamate receptor mediation on bone cells might also be involved in mechanically stimulated osteogenesis. In this study, we investigated the changes of bone formation and the expressions of...
Paper Details
Title
Down-regulation of N-methyl D-aspartate receptor in rat-modeled disuse osteopenia
Published Date
Jul 5, 2005
Volume
16
Issue
12
Pages
1780 - 1788
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