Maternal serum sFlt‐1/PlGF ratio in twin pregnancies with and without pre‐eclampsia in comparison with singleton pregnancies

Objective In singleton pregnancies, soluble fms‐like tyrosine kinase‐1 ( sFlt ‐1), placental growth factor ( PlGF ) and the sFlt ‐1/ PlGF ratio have shown utility as a diagnostic test for pre‐eclampsia ( PE ). The objective of this study was to characterize the maternal serum levels of sFlt ‐1, PlGF and sFlt ‐1/ PlGF ratio in normal and pre‐eclamptic twin pregnancies. Methods In a European multicenter case–control study, 49 women with a twin...