Impact of [18F]FDG PET imaging parameters on automatic tumour delineation: need for improved tumour delineation methodology

Delineation of tumour boundaries is important for quantification of [(18)F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) studies and for definition of biological target volumes in radiotherapy. Several (semi-)automatic tumour delineation methods have been proposed, but these methods differ substantially in estimating tumour volume and their performance may be affected by imaging parameters. The main purpose of this study was...