Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase
Abstract
A research team led by Renier Brentjens offers a new approach to monitor in vivo trafficking of T cells by tagging them for bioluminescence imaging using a membrane-anchored form of the humanized Gaussia luciferase enzyme. The set-up provides a high bioluminescent signal and should be useful for studying in vivo T cell function in mouse models of disease investigating mouse or human primary T cells. We developed a new approach to bioluminescent...
Paper Details
Title
Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase
Published Date
Feb 15, 2009
Journal
Volume
15
Issue
3
Pages
338 - 344
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