β-Catenin Is Required for the Tumorigenic Behavior of Triple-Negative Breast Cancer Cells
Abstract
Our previous data illustrated that activation of the canonical Wnt signaling pathway was enriched in triple-negative breast cancer and associated with reduced overall survival in all patients. To determine whether Wnt signaling may be a promising therapeutic target for triple-negative breast cancer, we investigated whether β-catenin was necessary for tumorigenic behaviors in vivo and in vitro. β-catenin expression level was significantly reduced...
Paper Details
Title
β-Catenin Is Required for the Tumorigenic Behavior of Triple-Negative Breast Cancer Cells
Published Date
Feb 6, 2015
Journal
Volume
10
Issue
2
Pages
e0117097 - e0117097
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