Loeys-Dietz syndrome

A 3-month-old boy presented with respiratory tract infection and was found to have a posterior mediastinal mass on chest radiography. CT of the chest (Fig. 1) showed an aortic dissection in the descending thoracic aorta causing a pseudoaneurysm measuring approximately 4×4 cm. The child had a family history of intracranial aneurysms. MR angiography of the head (Fig. 2) showed elongated, tortuous intracranial vessels. The child also had a bifid...