Genetics and molecular pathogenesis of pheochromocytoma and paraganglioma
Abstract
Although most pheochromocytomas (PCCs) and paragangliomas (PGLs) are sporadic, molecular genetic medicine has revealed that a considerable number of patients with apparently sporadic PCC actually have a genetic predisposition to the development of these tumors. After decades of intensive research, several genes are now known to play an important role in the pathogenesis of PCC. At present, these are RET proto-oncogene, von Hippel-Lindau disease...
Paper Details
Title
Genetics and molecular pathogenesis of pheochromocytoma and paraganglioma
Published Date
Jan 7, 2013
Journal
Volume
78
Issue
2
Pages
165 - 175
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