Effect of substitution degree of 2-hydroxypropyl-β-cyclodextrin on the alkaline hydrolysis of cinnamaldehyde to benzaldehyde

The yield of benzaldehyde in the 2-hydroxypropyl-β-cyclodextrin (2-HP-β-CD), with a low degree of substitution (DS = 3.9), catalytic system was 70%, which was higher than that of the system with 8.8 DS under the optimised conditions (323 K, 2% NaOH (w/v), cinnamaldehyde:2-HP-β-CD = 1:1 (molar ratio)). Due to the structural complementary effects of the host and guest, cyclodextrins (CDs) played the catalysis role in the reaction, which was...