Tight glycaemic control is a key factor in wound healing enhancement strategies in an experimental diabetes mellitus model

Diabetes mellitus is a leading cause of impaired wound healing. The aim of this study was to establish a glucose-controlled diabetic wound healing model. Sprague–Dawley rats were divided into three groups: Control group (C), Diabetic Non-glucose Controlled group (DNC) and Diabetic glucose Controlled group (DC). Glucose control was achieved using Insulman Rapid (average daily glucose level <10 mmol/L). 18 Sprague–Dawley rats underwent a dorsal...