Receptors involved in cell activation by antiphospholipid antibodies.
Abstract
The antiphospholipid syndrome (APS) is an autoimmune disease associated with arterial or venous thrombosis and/or recurrent fetal loss and is caused by pathogenic antiphospholipid antibodies (aPLA). The plasma protein β2-glycoprotein 1 (β2GP1) has been identified as a major target of aPLA associated with APS. Cell activation by aPLA appears to be a major pathogenic cause in the pathogenesis of APS. Receptors, co-receptors and accessory molecules...
Paper Details
Title
Receptors involved in cell activation by antiphospholipid antibodies.
Published Date
Oct 1, 2013
Journal
Volume
132
Issue
4
Pages
408 - 413
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Notes
History