Effects of current and former cigarette smoking on the clinical course of Crohn’s disease

Cigarette smoking is associated with a more severe course of Crohn's disease, but individual factors determining this effect are poorly known and it is not clear whether smoking cessation is associated with an improvement in the disease activity.To assess the factors determining the harmful effect of smoking in individuals with Crohn's disease.A total of 622 consecutive patients with Crohn's disease and Crohn's disease activity index <200 were...