Notch Signaling in Development and Cancer
Abstract
Notch is an evolutionarily conserved local cell signaling mechanism that participates in a variety of cellular processes: cell fate specification, differentiation, proliferation, apoptosis, adhesion, epithelial-mesenchymal transition, migration, and angiogenesis. These processes can be subverted in Notch-mediated pathological situations. In the first part of this review, we will discuss the role of Notch in vertebrate central nervous system...
Paper Details
Title
Notch Signaling in Development and Cancer
Published Date
Apr 4, 2007
Journal
Volume
28
Issue
3
Pages
339 - 363
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