Myopathy and eosinophilic pneumonia coincidentally induced by treatment with daptomycin.

Published on Jan 1, 2015in Internal Medicine1.005
· DOI :10.2169/INTERNALMEDICINE.54.3397
Hideharu Hagiya3
Estimated H-index: 3
(Okayama University),
Kou Hasegawa5
Estimated H-index: 5
(Okayama University)
+ 7 AuthorsFumio Otsuka35
Estimated H-index: 35
(Okayama University)
: A 34-year-old man with 22q11.2 deletion syndrome (DiGeorge syndrome) concurrently suffered from myopathy and eosinophilic pneumonia shortly after receiving daptomycin (DAP) for right-sided infective endocarditis. The simultaneous occurrence of these phenomena in relation to DAP therapy has not been previously well described. An allergic reaction was suspected as a possible etiology of these DAP-related complications. This case highlights the need for close observation in order to detect both musculoskeletal and respiratory disorders from the start of DAP therapy. Physicians should pay more attention to this new drug, which is expected to be frequently used in various clinical settings.
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