Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation

Volume: 112, Issue: 5, Pages: 1607 - 1612
Published: Jan 20, 2015
Abstract
Significance Mammalian hibernators can reduce their metabolic rate by 95% and body temperature to 2 °C. However, their central and peripheral nervous systems retain activity even in cold, through unknown mechanisms. We report here that neurons from hibernating squirrels express uncoupling protein 1 (UCP1), a protein known as a heat generator in brown adipose tissue. We show that squirrel UCP1 acts as the typical thermogenic protein and is...
Paper Details
Title
Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation
Published Date
Jan 20, 2015
Volume
112
Issue
5
Pages
1607 - 1612
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