Fluid shear in viscous fibronectin gels allows aggregation of fibrous materials for CNS tissue engineering
Abstract
Fibronectin (Fn) materials prepared from human plasma have been used in various forms as substrates for tissue engineering. Such purposes require that the soluble protein aggregates into insoluble fibrous structures which encourage the attachment and migration of cells. The method of aggregation due to mechanical shear was investigated by applying fluid shear forces directly to a viscous solution of Fn. Structural analysis revealed that...
Paper Details
Title
Fluid shear in viscous fibronectin gels allows aggregation of fibrous materials for CNS tissue engineering
Published Date
Jun 1, 2004
Journal
Volume
25
Issue
14
Pages
2769 - 2779
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