Insulin Resistance in Nonobese Patients with Polycystic Ovary Syndrome

<i>Objectives:</i> Most patients with polycystic ovary syndrome (PCOS) are obese and known to have insulin resistance. Obesity per se is a cause of insulin resistance. This study was performed to determine whether insulin resistance occurs in patients with PCOS in the absence of obesity and acanthosis nigricans. <i>Method:</i> For this purpose, an euglycemic hyperinsulinemic clamp study was performed in 12 nonobese...